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Research paper : Mental fatigue measurement as application software on consumer devices (S. IWAKI et al.)−216−Synthesiology - English edition Vol.7 No.4 (2015) among workers. These topics are also important to enhance the range of application of this technology, and we plan to continue developing the data analysis algorithms and collecting long-term data in various environments through close collaboration with industries including the venture company for technology transfer from AIST.AcknowledgementsPart of this research was conducted with the research grant from the Mitsui Sumitomo Insurance Welfare Foundation (FY 2011) and the science and technology grant from the Suzuki Foundation (FY 2011~2012), and with the support of the Start-up Development Strategy Task Force, Venture Development Center, AIST (FY 2008~2009).References[1]Jidosha Unso Jigyo Ni Kakawaru Kotsu Jiko Yoin Bunseki Hokokusho, Heisei 19 Nendo (Report on the Analysis of Causes of Traffic Accidents in Automotive Transportation Enterprises, FY 2007), Committee on the Analysis of Causes of Traffic Accidents in Automotive Transportation Enterprises, Ministry of Land, Infrastructure, Transport and Tourism (2008) (in Japanese).[2]N. Tachi: Shinban “Jikakusho Shirabe” no teian to kaitei sagyo keika (Proposals for new edition “Jikakusho Shirabe (survey of subjective symptoms)” and work progress), Digest of Science of Labour, 57 (5), 299-304 (2002) (in Japanese).[3]M. Kuroda, T. Ishizaki, T. Maruyama, Y. Takatsuka and T. Kuboki: Effect of dried-bonito broth on mental fatigue and mental task performance in subjects with a high fatigue score, Physiol. Behav., 92 (5), 957-962 (2007).[4]K. Saito: Measurement of fatigue in industries, Indust. Health, 37, 134-142 (1999).[5]L. R. Hartley, P. K. Arnold, G. Smythe and J. Hansen: Indicators of fatigue in truck drivers, Appl. Ergonomics, 25 (3), 143-156, (1994).[6]Y. Kaseda, C. Jiang, K. Kurokawa, Y. Mimori and S. Nakamura: Objective evaluation of fatigue by event-related potentials, J. Neurol. Sci., 158 (1), 96-100 (1998).[7]E. Simonson and N. Enzer: Measurement of fusion frequency of flicker as a test of fatigue of the central nervous system, J. Indust. Hyg. 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Fujita: Fluctuation of serum vitamin E (alpha-tocopherol) concentrations during exacerbation and remission phases in patients with chronic fatigue syndrome, Heart and Vessels, 25 (4), 319-323 (2010).[12]W. Karwowski (ed.): International Encyclopedia of Ergonomics and Human Factors, 2nd Edition, CRC Press, (2006).[13]K. Hashimoto: Physiological meaning of the critical flicker frequency (CFF) and some problems in their measurement: Theory and practice of the flicker test, Jap. J. of Indust. Health, 5 (9), 563-578 (1963) (in Japanese).[14]K. Hashimoto: Measurement of general fatigue, Ergonomics, 17 (3), 107-113 (1981) (in Japanese).[15]S. Hecht and C.D. Verrijp: The influence of intensity, color and retinal location on the fusion frequency of intermittent illumination, Proc. Natl. Acad. Sci., 19 (5), 522-535 (1933).[16]S. Hecht and C.D. Verrijp: Intermittent stimulation by light: IV. A theoretical interpretation of the quantitative data of flicker, J. General Physiol., 17 (2), 269-282 (1933).[17]S. Iwaki and N. Harada: Mental fatigue measurement based on the changes in flicker perception threshold using consumer mobile devices, Adv. Biomed. Eng., 2, 137-142 (2013).[18]Flicker Health Management Co., Ltd.: Top page, http://www.fhm.co.jp/,[19]Flicker Health Management Co.,Ltd.: Application page,https://play.google.com/store/apps/details?id=fhm.lite.application,[20]Flicker Health Management Co., Ltd.: iTunes preview, https://itunes.apple.com/jp/app/fhm-lite/id630387485?mt=8 [21]M. Shichiri, N, Harada, N. Ishida, L.K. Komaba, S. Iwaki, Y. Hagihara, E. Niki and Y. Yoshida: Oxidative stress is involved in fatigue induced by overnight deskwork as assessed by increase in plasma tocopherylhydroqinone and hydroxycholesterol, Biol. Psychol., 94 (3), 527-533 (2013).AuthorsSunao IWAKICompleted the doctorate course at the Graduate School of Engineering, The University of Tokyo in 1998. Ph.D. in Engineering. Joined the Electrotechnical Laboratory in 1998. Currently, Leader of Cognition and Action Research Group, Human Technology Research Institute, AIST. Professor of Collaborative Graduate Program, Graduate School of Comprehensive Human Sciences, University of Tsukuba. Engages in the development of highly accurate, non-invasive visualization of human brain activity, its application to the objective evaluation of subjective perception and cognition, and the R&D of physiological and psychological index that can be used in daily life. In this paper, was in charge of the development of measurement algorithm for flicker perception threshold without arbitrariness to implement the fatigue measurement system on the general-purpose devices that can be used in daily life, and the drafting of the paper.Nobuyoshi HARADACompleted the doctorate program at the Graduate School of Environmental Sciences, Hokkaido University in 1996. Ph.D. in Environmental Sciences. After serving as JST Fellow at National Institute of Biosciences and Human Technology, CREST Fellow, and NEDO Fellow, became the AIST Fellow in 2004. In 2010, became President of Flicker Health

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