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Research paper : Development of methane hydrate production method (J. Nagao)−94−Synthesiology - English edition Vol.5 No.2 (2012) Obtained at the Eastern Nankai Trough, Japan, Energy & Fuels, 24, 6353 (2010).[15]Y. Konno, Y. Masuda, H. Oyama, M. Kurihara and H. Ouchi: Numerical Analysis on the Rate-Determining Factors of Depressurization-Induced Gas Production from Methane Hydrate Cores, Proc. Offshore Technology Conference 2010, 20591 (2010).[16]J. Schicks, E. Spangenberg, R. Giese, B. Steinhauer, J. Klump and M. Luzi: New Approaches for the Production of Hydrocarbons from Hydrate Bearing Sediments, Energies, 4, 151 (2011). AuthorJiro NagaoCompleted the two-years masters course at the Graduate School of Engineering, Hokkaido University in 1991. Joined the Government Industrial Research Institute, Hokkaido, Agency of Industrial Science and Technology, Ministry of International Trade and Industry in 1991 (current AIST). Received Doctor (Engineering) in 2000 from Hokkaido University. Became the leader of the Production Technology Team, Methane Hydrate Research Center in 2009. Also became the leader of the Research Group for Production Method and Modeling of the MH21 Research Consortium in 2010. Engaged in research of physics and chemistry of clathrate materials and development of production method and modelling of gas hydrate resources. Discussions with Reviewers1 General construction of the manuscriptComment (Hiroshi Tateishi, AIST)For the development of the gas production technology from methane gas hydrate reservoirs, this manuscript first explains the overview of Japan’s Methane Hydrate Research and Development Program, and then the development of the apparatus for methane hydrate production tests carried out by the author is described. The construction of the manuscript is rather unusual, because the experimental results from the apparatus have not yet been obtained at present. In spite of this fact, the manuscript is acceptable after revision because publication of such type of manuscript is requested from the outside. From the standpoint of the journal, Synthesiology, the manuscript lacks issues as pointed out in the following comments. From the viewpoint of “synthesis,” there is a dual structure of synthesis: one is micro-level technology synthesis to integrate elemental technologies toward the development of the apparatus which is the main purpose of the present manuscript, and the other is macro-level system synthesis to integrate the results obtained with the apparatus toward the development of the production system. For the revision of the manuscript, please take these points into consideration.Answer (Jiro Nagao)Concerning the development of a large-scale laboratory apparatus for the optimization of production conditions toward commercial utilization of methane hydrate, the outline of the program, the R&D issues of the Research Group for Production Method and Modeling of MH21 Consortium coordinated by the MHRC at AIST, and the important issues to be analyzed with this apparatus have been described. In response to the reviewer’s TerminologyTerm 1.Darcy (D): a traditional unit for permeability. The SI unit for pearmeability is m2. 1D is ca. 10-12 m2.References[1]M. Satho: Distribution and resources of marine natural gas hydrates around Japan, Proc. 4th Int. Conf. Gas Hydrate, 175 (2002).[2]F. Colwell, R. Matsumoto and D. Reed: A review of the gas hydrates, geology, and biology of the Nankai Trough, Chemical Geology, 205, 391 (2004).[3]Bottom simulating reflector (BSR) is observed in seismic profile data, which broadly mimics the relief of the sea floor. This boundary is to mark the pressure and temperature dependent base of the methane-hydrate stability field. Namely, above the BSR, methane hydrate exists as hydrate.[4]M. Kida, K. Suzuki, T. Kawamura, H. Oyama, J. Nagao, T. Ebinuma, H. Narita, H. Suzuki, H. Sakagami and N. Takahashi: Characteristics of natural gas hydrates occurring in pore spaces of marine sediments collected from the eastern Nankai Trough, off Japan, Energy & Fuels, 23, 5580 (2009).[5]E. D. Sloan: Clathrate Hydrates of Natural Gases, 2nd ed., Marcel Dekker (1998).[6]M. Kurihara, A. Sato, H. Ouchi, H. Narita, Y. Masuda, T. Saeki and T. Fujii: Prediction of gas productivity from Eastern Nankai Trough methane-hydrate reservoirs, Offshore Technology Conference, SPE international, Society of Petroleum Engineers, OTC-19382 (2008).[7]M. H. Yousif, P. M. Li, M. S. Selim and E. D. Sloan: Depressurization of natural gas hydrates in Berea sandstone cores, Journal of Inclusion Phenomena and Molecular Recognition in Chemistry, 8, 71 (1990).[8]Y. Kamata, T. Ebinuma, R. Omura, H. Minagawa and H. Narita: Decomposition behaviour of artificial methane hydrate sediment by depressurization method, Proc. 5th Int. Conf. Gas Hydrate, 3016 (2005).[9]T. J. Kneafsey, L. Tomutsa, G. J. Moridis, Y. Seol, B. M. Freifeld, C. E. Taylor and A. Gupta: Methane hydrate formation and dissociation in a partially saturated core-scale sand sample, Journal of Petroleum Science & Engineering, 56, 108 (2007).[10]H. Oyama, Y. Konno, Y. Masuda and H. Narita: Dependence of depressurization-induced dissociation of methane hydrate bearing laboratory cores on heat transfer, Energy & Fuels, 23, 4995 (2009).[11]Detail and research planning of the Japan’s Methane Hydrate Research and Development Program and research scheme of Research Consortium for Methane Hydrate Resources in Japan (MH21 Research Consortium) are described at http://www.mh21japan.gr.jp/english/. [12]Y. Konno, Y. Masuda, Y. Hariguchi, M. Kurihara and H. Ouchi: Key Factors for Depressurization-Induced Gas Production from Oceanic Methane Hydrates, Energy & Fuels, 24, 1736 (2010).[13]H. Oyama, J. Nagao, K. Suzuki and H. Narita: Experimental Analysis of Sand Production from Methane Hydrate Bearing Sediments Applying Depressurization Method, J. MMIJ, 126, 497-502 (2010) (in Japanese).[14]Y. Konno, H. Oyama, J. Nagao, Y. Masuda and M. Kurihara: Numerical Analysis of the Dissociation Experiment of Naturally Occurring Gas Hydrate in Sediment Cores

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