Our research group has succeeded in building a continuous-flow device that generates hyperpolarized xenon gas with a high efficiency and in developing the device into a commercialized, compact, automated high-performance system. The new device is a result of efforts to increase the level of sophistication of a continuous-flow system for the generation of hyperpolarized xenon gas in nuclear magnetic resonance (NMR) for medical use. In addition to being smaller in size, the device can be connected directly to an NMR apparatus by using simple capillaries. It is expected to be useful in the analysis of pore structures of nanoporous materials such as those used in fuel cells, and in medical diagnosis technology using sensitive magnetic resonance imaging (MRI) system.