Like proteins and nucleic acids, glycans, the third class of repeating biopolymers, have essential roles in living organisms. However, tools to synthesize and analyse the glycans have been lacking. Research Center for Glycoscience in AIST has successfully developed three important tools for glycomics research; a glycogene library, a preparation robot for the glycan library, and a rapid and sensitive analyzing system for glycans. Exploring the perplexities of life which cannot be explained with nucleic acids and proteins will be accelerated by using these innovative tools.