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AIST TODAYNo.19 Winter 2006 [ PDF:17.6MB ]

Contents List Message:Full Research as a Growth Medium for Researchers Feature:Health and Science Technology Research Hot Line In Brief

Multi Cell Sorter on a Chip
Ken Hirano
Health Technology Research Center
e-mail address

We have developed a new method of particle retrieve for a chip-based multi-cell sorter. Optical gradient force can change direction of target dielectric particles, such as cells, and retrieve particles against hydorodynamic force by irradiaton of a laser in a microfluidics device. We are putting the developed method to practical use of a multi-cell sorter in a chip for applications of life science and medical technology.
Figure1
 Figure2
Figure 1: Concept of optical sorting. A dielectric particle such as biological cell, is moved to laser beam focus by optical gradient force, when the particle comes into beam irradiated region.
Figure 2: Sequential photographs of a single 2µm bead recovery by focused Nd:YAG laser (1064nm in wavelength) denoted as black arrow. The bead was deflected to vertical direction against flow one by optical gradient force (white arrow).

Relational Information

AIST TODAY Vol.5 , No.10 (2005) p.22-23

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