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AIST TODAYNo.12 Spring 2004


Glycan Profiling by Frontal Affinity Chromatography
- Development of an automated machine in the context of structural glycomics -


To understand glycan functions, it is essential to get basic information about complex glycan structures. For this purpose, we are developing a "glycan profiler" under the concept that lectins are "decoderproteins for glycomics". FAC (frontal affinity chromatography) is the first choice for precise determination of affinity constants between lectins and glycans in a highly sensitive and high-throughput manner.

Figure
Outline of the automated analyzer FAC-1, a proto type machine for frontal affinity chromatography (above) and the inside view of the machine

Relational Information

AIST Today Vol. 4, No.1 (2004) 12



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